Gambaran Kadar Hormon Tiroid (FT4 dan TSH) Serta Kejadian Takikardia pada Pasien Hipertiroid Dewasa

Bianca Ferty Feryona; Eko Siswanto; Abdul Wahab

doi:10.55606/jurrike.v5i2.10038

Authors

Bianca Ferty Feryona Universitas Abulyatama
Eko Siswanto Universitas Abulyatama
Abdul Wahab Universitas Abulyatama

DOI:

https://doi.org/10.55606/jurrike.v5i2.10038

Keywords:

Cross-Sectional Study, FT4, Hyperthyroidism, Tachycardia, TSH Hormone Levels

Abstract

Hyperthyroidism is a condition in which the thyroid gland produces excessive amounts of the hormone thyroxine, causing the body's metabolism to accelerate. Diagnosis is established through physical examinations and blood tests to measure thyroid hormone levels, specifically Free Thyroxine (FT4) and Thyroid Stimulating Hormone (TSH). This condition can lead to cardiovascular disorders such as rapid heart rate (tachycardia), palpitations and the risk of arrhythmia. The purpose of this study was to determine the profile of thyroid hormone levels (FT4 and TSH) and the incidence of tachycardia in adult hyperthyroid patients. This was a descriptive observational study with a cross-sectional design. The population consisted of all 50 hyperthyroid patients, selected using a total sampling technique. The data collection instrument utilized observation sheets. This research was conducted at Pertamedika Ummi Rosnati Hospital from March 1 to April 30, 2026. Data analysis involved calculating the percentage and frequency of each research variable. The results showed that the incidence of tachycardia accounted for 31 respondents (62.0%), while a normal pulse rate was found in 19 respondents (38.0%). High FT4 thyroid hormone levels were observed in 38 respondents (76.0%), and normal levels in 12 respondents (24.0%). Low TSH thyroid hormone levels were found in 43 respondents (86.0%), and normal levels in 7 respondents (14.0%). Based on the results, it can be concluded that the majority of hyperthyroid patients experienced tachycardia, elevated FT4 levels, and decreased TSH levels.

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References

Ahyar, H. (2020). Buku Metode Penelitian Kualitatif & Kuantitatif. CV. Pustaka Ilmu Group, Yogyakarta.

Akbar, F, Maulana, R, Fitriyah, H. (2018). Sistem Monitoring Denyut Jantung Menggunakan Node MCU dan MQTT. Jurnal Pengembangan Teknologi Informasi dan Ilmu Komputer Universitas Brawijaya. 2(12): 5969-5976. https://j-ptiik.ub.ac.id/index.php/j-ptiik/article/view/3480/1366

Aliffani, M,F., Irfani, F,N., Novalina, D. (2025). Gambaran Pemeriksaan Imunologi terhadap Pasien Tirotoksikosis di Rumah Sakit PKU Muhammadiyah Yogyakarta Periode 2020-2025. Malahayati Nursing Journal. 7(12):5503-5514. https://doi.org/10.33024/mnj.v7i12.23494

Alwi, I, Setiati, S, Sudoyo, A, W, Simadibrata, M. (2024). Buku Ajar Ilmu Penyakit Dalam. Interna Publishing, Jakarta.

Amalia, M., Martafari, C, A., Emiralda, E. (2023). Faktor Risiko Kejadian Hipertiroid di Rumah Sakit Meuraxa Banda Aceh. Jurnal Kesehatan Tambusai. 4(3):2679-2686. https://doi.org/10.31004/jkt.v4i3.17490

American Thyroid Association (ATA). (2023). Hyperthyroidism. https://www.thyroid.org/hyperthyroidism/.

Arianti. K, Y., Sherlyna. P, I., Hakim, N. R. (2021). Hubungan Dukungan Keluarga Dengan Tingkat Kecemasan Pasien Pre Operasi Thyroiektomy di Klinik Bedah RSD Mangunsada Kabupaten Bandung. Jurnal Nursing Update 12 (1): 22-34. https://stikes-nhm.ejournal.id/NU/article/view/307/278.

Go, M, T., George, A, M., Tahsin, B., Fogelfeld, L. (2022). Tachycardia in hyperthyroidism. Not So Common. PLoS One. 17:1-10. doi:10.1371/journal.pone.0273724

Habibie, M. (2020). Manifestasi Klinis dan Tatalaksana Penyakit Jantung Tiroid. Jurnal Kedokteran Nanggroe Medika. 3(1):39-46. https://doi.org/10.35324/jknamed.v3i1.181

Harfana, C., Rosidi, A., Ulvie, N, Y., Sulistiani, P. (2021). TSH dan FT4 Dengan Indeks Massa Tubuh (IMT) pada Pasien Dewasa: Studi Cross-Sectional di Klinik Litbangkes Magelang. Jurnal MGMI 13 (1). https://Doi.Org/10.22435/Mgmi.V13i1.4841;Co pyright

Harfana, C., Rosidi, A., Ulvie, Y, N, S., Sulistiani, R, P. (2021). TSH dan FT4 Dengan Indeks Massa Tubuh (IMT) pada Pasien Dewasa Studi Cross-Sectional di Klinik Litbangkes Magelang. Media Gizi Mikro Indonesia. 13(1):11-24. https://doi.org/10.22435/mgmi.v13i1.4841

Husodo, D, P., Pramudiantara, G, N., Wibawa, G, E., Suryantarini, N,W,P., Widad, N & Bramantyo, R. (2026). Diagnosis and Comprehensive Management of Thyroid Stom: A Literature Review. Jurnal Ilmu Kedokteran dan Kesehatan. 13(4):910-919. https://doi.org/10.33024/jikk.v13i4.23240

Karlindo, S, M, & Winarno. (2024). Krisis Tiroid Dengan Fibrilasi Atrium. Jurnal Ners. 8(2):1937-1940. https://doi.org/10.31004/jn.v8i2.26382

Khan, R., Sikanderkhel, S., Gui, J. (2020). Thyroid and Cardiovascular Disease: A Focused Review on The Impact of Hyperthyroidism in Heart Failure. Cardiology Research. 11(2):68-75. doi:10.14740/cr1034

Khurana, N, K, Kumar S, Kumar S, Kumar P, Rizwan A. (2021). Frequency of Cardiovascular Manifestation in Patients with Hyperthyroidism. Journal Cureus. 13(1):1-4. doi:10.7759/cureus.12839

Mathew P, Kaur J, Rawla P. (2023). Hyperthyroidism. Jurnal National Library of Medicine. https://www.ncbi.nlm.nih.gov/books/NBK537053/

Meutia S, & Trianda R. (2024). Pria 41 Tahun Dengan Struma Nodusa Hipertiroidisme dan Hepatoma. Jurnal Ilmu Kedokteran dan Kesehatan. 3(1):107-118. https://doi.org/10.55606/klinik.v3i1.2259

Meutia, S, & Yuanita, A. (2023). Tirotoksikosis. Galenical: Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh. 2(6): 54-64. https://doi.org/10.29103/jkkmm.v2i6.11277.

Neves, JS, Fontes-Carvalho R, Borges-Canha M, et al. (2021). Thyroid Hormones within The Normal Range and Cardiac Function in The General Population: The EPIPorto Study. European Thyroid Journal. 10(2):150-160. doi:10.1159/000508407

Ningsih, W, E, S & Ismawatie, E. (2023). Korelasi Kadar TSH dan FT4 pada pasien Tiroid di Kabupaten Bangkalan. Plenary Health Jurnal Kesehatan Paripurna. 1 (3): 244-249. https://doi.org/10.37985/plenaryhealth.v1i3.592

Pratomo, B, Y., Widodo, U., Ferdiansyah, D. (2022). Manajemen Preoperatif pada Pasien Hipertiroid. Jurnal Komplikasi Anestesi. 9(3): 60-66. https://doi.org/10.22146/jka.v9i3.8332

Prumnastianti G., Setyo S, N, H, Y., Santoso, D, Santosa, R,I. (2021). Relationship Between Thyroid Function Disorders and LDL-Cholesterol Levels. Journal Sain Health 5(2): 6-12. https://doi.org/10.51804/jsh.v5i2.1018.6-12

Putri, A, S & Budiarti, A. (2022). Atrial Fibrilasi pada Hipertiroid: Diagnosis dan Penatalaksanaan. Jurnal Continuing Medical Education 14 (2). 670-680. https://proceedings.ums.ac.id/kedokteran/article/view/2158

Putri, E, O., Aldo, A, Sawal, D, Lisan, M,I, Sunaidi, Y. (2024). Analisis Retrospektif Profil Tiroid (Thyroid Stimulating Hormone dan Free Thyroxine-4) dengan Metode Enzyme Linked Fluorescent Assay. Jurnal Analis Kesehatan Kendari. 8(1):33-45. doi:http://10.46356/jakk.v8i1.391

Putri, N, Y., Humardhanai, A., Kusmardi. (2025). Hipertiroid dan Badai Tiroid: Tinjauan Pustaka. Jurnal Riset Rumpun Ilmu Kedokteran, 4 (3). DOI: https://doi.org/10.55606/jurrike.v4i3.6984

Reza, Z, F & Suryana, T. (2022). Aplikasi Monitoring Kesehatan Dengan Memanfaatkan Smartwatch Berbasih Android. Jurnal Penelitian Mahasiswa Teknik dan Ilmu Komputer 2 (2): 85-92. https://garuda.kemdiktisaintek.go.id/documents/detail/3239056

Ribera, A, Zhang L, Ribeiro C, et al. (2023). Practical Considerations for Accurate Determination of Thyroxine by Equilibrium Dialysis. Journal of Mass Spectrometry Advances in the Clinical Lab 29:9-15. doi:10.1016/j.jmsacl.2023.06.001

Riset Kesehatan Dasar (RISKESDAS). (2013). Badan Penelitian dan Pengembangan Kesehatan. doi:10.1126/science.127.3309.1275

Rizka, P, C, T, W, Irfani, F,N, Bimantara, A. (2024). Gambaran Kadar Pemeriksaan Thyroid Stimulating Hormone (TSH) dan Free Thyroxine (FT4) pada Pasien Dengan Gangguan Tiroid di RSUD Bagas Waras Klaten. Jurnal Kesehatan Tambusai. 5(4):10698-10704. https://www.researchgate.net/publication

Russo, S, C, Salas-lucia F, Bianco AC. (2021). Deiodinases and the Metabolic Code for Thyroid Hormone Action. Endocrinology. 162 (8):1-13. doi:10.1210/endocr/bqab059

Shalih, M,G., Utami M, R., Adam, M,I., Shadrina, J, A. (2023). Edukasi Hormon Tiroid dan Antitiroid Terhadap Penyakit Gondok di SMK Wirasaba Karawang. Jurnal Dorkes (Dedikasi Olahraga dan Kesehatan), 1 (2): 50-57. https://journal.unsika.ac.id/index.php/dorkes/index

Siregar, J, H. (2020). Krisis Tiroid / Badai Tiroid. Jurnal Kedokteran Ibnu Nafis. 9(2):93-99. https://doi.org/10.30743/jkin.v9i2.335

Sudibia, N, K, M, P. (2024). Analisis Pemeriksaan Laboratorium pada Penyakit Tiroid. Jurnal Action Research Literate, 8 (8). https://arl.ridwaninstitute.co.id/index.php/arl

Tompo, K, U, M., Shafriani, N, R., Irfani, F, N. (2025). Gambaran Kadar TSH, FT3 dan FT4 pada Pasien Gangguan Tiroid di RSUD Anutaloko Parigi. Jurnal Ilmiah Kesehatan Masyarakat) 4 (3): 922-928. DOI: 10.55123/sehatmasv4i3.6023

Wang, C, Li Y, Teng D, et al. (2021). Hyperthyroidism Prevalence in China After Universal Salt Iodization. Frontiers Endocrinology (Lausanne).12: 1-11. doi:10.3389/fendo.2021.651534

Wenilia, R. (2024). Hypothyroid and Heart Disease. Jurnal Medika Hutama. 6(1): 4084-4095. https://jurnalmedikahutama.com/index.php/JMH/article/view/720

Yurizali, B., & Nurmaines. A. (2024). Profil Tingkat Hormon Stimulasi Tiroid dan Kondisi Kesehatan Dalam Studi Populasi Dewasa. Jurnal Kedokteran dan Kesehatan, 20 (1). 124-137. https://doi.org/10.24853/jkk.20.2.124-137

Zhang, Y, Wang Y, Liu M, et al. (2023). The Value of FT4 / TSH Ratio in The Differential Diagnosis of Graves’ Disease and Subacute Thyroiditis. Frontiers Endocrinology (Lausanne). 14:2. doi:10.3389/fendo.2023.1148174