Formulasi Gel Sabun Wajah Ekstrak Etanol Daun Putihan (Chromolaena odorata L.) Sebagai Antijerawat

Authors

  • Monica Suryani Univesitas Sari Mutiara Indonesia
  • Manahan Situmorang Univesitas Sari Mutiara Indonesia
  • Steven Tandiono Univesitas Sari Mutiara Indonesia

DOI:

https://doi.org/10.55606/jikg.v1i1.959

Keywords:

Gel, Putihan Leaf, Antibacterial

Abstract

Acne is a skin disease due to chronic inflammation with complex pathogenesis. The public has empirically used the white plant to treat wounds on the skin, it contains flavonoids, saponins, and tannins which can protect the skin from bacteria and can inhibit bacterial growth. This study aims to test the antibacterial activity against Propionibacterium acnes. The ethanol extract of Putihan leaves was obtained by maceration using 96% ethanol solvent, formulated and evaluated for facial soap gel preparations of ethanol extract of Putihan leaves with various extract concentrations of 0% (F0), 10% (F1), 13% (F2), and 15% (F3) which testing antibacterial activity against Propionibacterium acnes. The results showed that the antibacterial activity of the facial soap gel preparation of ethanol extract of Putihan leaves with a concentration of 10% had an inhibition of 8.4 ± 0.20 mm, 13% had an inhibition of 9.5 ± 0.23 mm and 15% had an inhibition of 10.6 ± 0.64mm. Based on this description, the resulting gel preparation has antibacterial activity against Propionibacterium acne. The three formulas are included in the medium inhibition zone category, but the one with the broadest inhibition zone is at a concentration of 15%.

 

References

Adhi, D. et al. (2018) Ilmu penyakit Kulit Dan Kelamin. FKUI.

Afifi, R., Erlin, E., & Rachmawati, J. (2018). Uji Anti Bakteri Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L) Terhadap Zona Hambat Bakteri Jerawat Propionibacterium acnes Secara In Vitro. Quagga Jurnal Pendidikan dan Biologi, 10(01), 10–17.

Asbullah., Wulandini, P., Febrianita, Y., (2021). Farktor-Faktor Yang Mempengaruhi Terhadap Timbulnya Acne Vulgaris (Jerawat) Pada Remaja Di SMAN 1 Pelangiran Kabupaten Indragiri Hilir Tahun 2018. Jurnal Keperawatan Abdurrab Vol 04(2). Hal 79-88.

Daulay P. A., Rafita Y. (2022). Formulasi Sediaan Gel Hand Sanitizer Ekstrak Etanol Daun Tekelan (Chromolaena odorata L.) R. King & H. Rob Dan Uji Aktivitas Antibakteri Terhadap Staphylococcus Epidermidis. Journal of Health and Medical Science Vol 1, No 1, Hal 87-99.

Eugresya G, Avanti C, Uly SA. (2017). Pengembangan formula dan uji stabilitas fisik pH sediaan gel facial wash yang mengandung ekstrak etanol kulit kayu kesambi. Media Pharmaceutica Indonesia. 1(4):181-188.

Hidayatullah, M. E. (2018). Potensi Ekstrak Etanol Tumbuhan Krinyuh (Chromolaena odorata L) sebagai Senyawa Anti-Bakteri. Proceeding of The URECOL, 436-441.

Ismarani D, Pratiwi L, Kusharyanti I. (2014). Formulasi gel pacar air (Impatiens balsamina Linn.) terhadap Propionibacterium acnes dan Staphylococcus epidermidis. Pharmaceutical Sciences & Research. 1(1):30-45.

Komala O, Yulianita dan Rahmawati R. (2021). Aktivitas Ekstrak Etanol 96% Dan Fraksi Daun Kirinyuh (Chromolaena odorata L.) Terhadap Propionibacterium acnes. Jurnal Ilmiah Farmasi. 11(1) : Hal. 23-34

Movita, Theresia. (2013). Acne Vulgaris. Artikel Ilmiah Continuing Medical Education, CDK 203/Vol 40, No 4.

Rahmi, A.H., Cahyanto, T., Sujarwo, T., dan Lestari, I.R. (2015). Uji Aktivitas Antibakteri Ekstrak Daun Beluntas (Pluchea indica L) Terhadap Propionibacterium acnes Penyebab Jerawat. Jurnal ISTEK, Vol IX(1). Halaman 142-143.

Rohmani. S., Sonia Karunia N., Wening D.W., Dian Eka.E., Wisnu K. (2022). Pengaruh Variasi Konsentrasi Surfaktan Iselux Ultra Mild pada Formulasi Hydrating Facial Wash Potassium Azeloyl Diglycinate. Jurnal Kefarmasian Indonesia. 12(1):58-68.

Soesanto, A. and Riyanto, P. (2017). Pengaruh Pemberian Suplementasi Likopen Terhadap Derajat Keparahan Akne Vulgaris. Jurnal Kedokteran Diponegoro, 6(2), pp. 268–279.

Suryana. (2013). Kewirausahaan Kiat dan Proses Menuju Sukses. Salemba Empat.

Vijayaraghavan, K., Rajkumar, J. and Seyed, M. A. (2017) ‘Efficacy of Chromolaena odorata leaf extracts for the healing of rat excision wounds’, Veterinarni Medicina, 62(10), pp. 565– 578. doi: 10.17221/161/2016-VETMED.

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Published

2023-03-07

How to Cite

Monica Suryani, Manahan Situmorang, & Steven Tandiono. (2023). Formulasi Gel Sabun Wajah Ekstrak Etanol Daun Putihan (Chromolaena odorata L.) Sebagai Antijerawat. Jurnal Ilmu Kesehatan Dan Gizi, 1(1), 192–198. https://doi.org/10.55606/jikg.v1i1.959