Bidang kajian dalam jurnal ini termasuk sub rumpun Ilmu Kesehatan Umum,Ilmu Keperawatan dan Kebidanan, Ilmu Psikolog dan Ilmu Farmasi. Jurnal Riset Rumpun Ilmu Kesehatan menerima artikel dalam bahasa Indonesia dan diterbitkan 3 kali setahun: April, Agustus dan Desember. Print ISSN : 2828-9366, Online ISSN : 2828-9374 Jurnal ini terakreditasi SINTA 5 (Surat Keputusan Direktur Jenderal Pendidikan Tinggi, Riset, dan Teknologi Nomor 10/C/C3/DT.05.00/2025 tanggal 21 Maret 2025 tentang Peringkat Akreditasi Jurnal Ilmiah Periode I Tahun 2025) dimulai dari Volume 1 Nomor 2 Tahun 2022 sampai Volume 6 Nomor 1 Tahun 2027.
Hubungan Dukungan Keluarga, Kualitas Tidur, Stres Akademik dengan Gangguan Kecemasan pada Siswa SMAN 1 Sumbawa Besar
Anxiety disorders are common mental health problems among adolescents, particularly high school students who face academic demands, social pressure, and emotional changes. Family support, sleep quality, and academic stress are considered factors related to students’ anxiety levels. This study aimed to examine the relationship between family support, sleep quality, academic stress, and anxiety disorders among students of SMAN 1 Sumbawa Besar. An analytical study with a cross-sectional design was conducted involving 114 students selected through stratified random sampling. Data were collected using the Perceived Social Support–Family (PSS-Fa), Pittsburgh Sleep Quality Index (PSQI), Educational Stress Scale for Adolescence (ESSA), and Depression Anxiety Stress Scale (DASS-42). Bivariate analysis was performed using the chi-square test, while multivariate analysis employed binary logistic regression. Bivariate results indicated significant associations between family support, sleep quality, academic stress, and anxiety disorders (p < 0.05). However, multivariate analysis revealed that only family support and sleep quality were significantly associated with anxiety disorders, while academic stress was not significant after controlling for other variables. These findings suggest that anxiety prevention efforts should prioritize strengthening family support and improving sleep quality, alongside academic stress management within the school environment.
Copyright (c) 2026 JURNAL RISET RUMPUN ILMU KESEHATAN https://creativecommons.org/licenses/by-sa/4.0
Hubungan Motivasi Kerja dan Self Efficacy dengan Tingkat Burnout Perawat di Rumah Sakit Islam Sultan Agung Semarang
Burnout among nurses is a serious problem that can reduce the quality of nursing services and the well being of nurses. Work motivation and self efficacy are psychological factors that play an important role in reducing burnout. The aim is to minimize the occurrence of burnout among nurses in their performance.The purpose of this study is to determine the significance of the relationship between work motivation and self efficacy with the level of burnout among nurses. This research is quantitative in nature with a cross-sectional approach. Data collection was conducted using questionnaires administered to 98 respondents from the total population. The instruments used included a work motivation questionnaire (ERG), a general self-efficacy scale (GSES), and a Maslach Burnout Inventory (MBI). The data collected was processed using Spearman's test and ordinal logistic regression. Results researchers found that respondents who reported high work motivation numbered 89 respondents with a percentage of (90.8%), self-efficacy among nurses also showed a high category in 90 respondents with a percentage of (91.8%), and the majority of burnout levels were in the low category range of 65 respondents with a percentage of (66.4). Statistical tests showed a relationship between work motivation and burnout levels with a p-value of 0.000 (a = -0.358), and showed that there was a relationship between self-efficacy and burnout levels with a p-value of 0.013 (a = -0.250). Furthermore, multivariate statistics found that work motivation was the dominant factor influencing burnout with a p-value of 0.012 (E = -2.030). Conclusion there is a significant relationship between work motivation and self-efficacy with the level of burnout among nurses. Nurses with high work motivation and self-efficacy tend to have lower levels of burnout. Work motivation is a dominant factor in influencing burnout.
Pengaruh Pelatihan Pembuatan Makanan Pendamping (MP-ASI) Berbahan Herbal pada Ibu Batita terhadap Pengetahuan dan Keterampilan Pembuatan Makanan Pendamping (MP-ASI)
The provision of herbal-based complementary feeding (MP-ASI) has several positive impacts, including improving mothers’ understanding and skills in preparing complementary foods from local food ingredients in accordance with local customs and socio-cultural practices, thereby enabling mothers to independently continue providing local complementary feeding. This study aimed to determine the effect of training on the preparation of herbal-based complementary feeding for mothers of children under three years old on their knowledge and skills in preparing complementary feeding. This study employed a quasi-experimental research design and was conducted at Kanda Public Health Center. The population consisted of all mothers with children under three years old in the working area of Kanda Public Health Center, totaling 245 mothers. The sample size in this study was 35 respondents. The results of the analysis showed that there was a significant difference in mothers’ knowledge before and after the training on complementary feeding preparation, with a significance value of 0.000.
Comparison of the Effects of Intratecal Morphine Administration and Transversus Abdominis Muscle Block as Post-Caesari Section Analgesics
The problem that is often faced by patients after cesarean section surgery is pain in the operating area, many therapies are used to reduce pain scores in patients. From non-medical mentosa, medical therapy to pain intervention. Two of the methods to reduce postoperative cesarean section pain are intrathecal morphine injections and transversus abdominis muscle blocks (TAP blocks). This study aims to find differences in pain scores after sectio caesaria surgery between patients who received intrathecal morphine and patients who received TAP block. An experimental study used the Post Test Only Control Group Design on Dirgahayu Hospital patients. A total of 108 patients were divided into 3 groups. Group K was not intervened by pain, group B was intervened by TAP block, group M was intervened with intrathecal morphine injection. VAS score was measured at the 4th hour postoperatively. Data were analyzed with the One-Way ANOVA test followed by the Post Hoc Test Bonferroni. Lower pain score was obtained in the group that received pain intervention than the control group with a significant difference (p<0.05). The pain scores of patients who received TAP block were lower than those who received intrathecal morphine with a significant difference (p<0.05). There was a significant difference in pain scores between intrathecal morphine and TAP block. It is hoped that TAP block administration will be used to reduce the pain scale after sectio caesaria surgery. Further research is needed regarding these 2 methods.
Efektivitas Program Fisioterapi pada Pasien Pasca Spondilitis Tuberkulosis di Rumah Sakit Paru Ario Wirawan Salatiga
This case report examines the effectiveness of a combined pulmonary rehabilitation and musculoskeletal physiotherapy program for a 26-year-old male post-pulmonary tuberculosis patient with lumbar tuberculous spondylitis. The patient, who had completed anti-tuberculosis treatment, presented with low back pain, shortness of breath, fatigue, and limited mobility. Spirometry indicated severe restrictive ventilatory impairment (FVC 1.28 L, 32% of predicted), and lower extremity muscle strength was reduced (MMT 2-3/5). The patient used a TLSO brace and walking aid. Over a three-week physiotherapy program, the patient participated in breathing exercises, spinal mobilization, muscle strengthening, functional exercises, and education on brace use. Evaluation occurred at the first, second, and third weeks. After treatment, pain intensity decreased from VAS 6 to VAS 3, FVC improved to 1.72 L, chest expansion increased, muscle strength improved to MMT 4/5, and performance on the Five-Times Sit-to-Stand Test showed progress. The Functional Independence Measure (FIM) score increased from 98 to 115, reflecting improved functional independence. These findings suggest that the combination of pulmonary and musculoskeletal physiotherapy effectively improved respiratory function, muscle strength, and the patient’s overall functional capacity.
Hubungan Pengetahuan dengan Sikap Tentang Sadari pada Remaja Putri Kelas X di MAN 3 Sleman
According to the International Agency for Cancer Registry (IACR), breast cancer is the most common cancer among women after lung cancer, and continues to be frequently diagnosed worldwide. In 2022, more than 2.32 million new cases of breast cancer were reported globally, while Indonesia recorded 65,858 cases (16.6% of all cancers). Therefore, adolescent girls need to have adequate knowledge and a positive attitude toward breast self-examination (BSE/SADARI) as part of reproductive health awareness and preventive efforts. This study aims to examine the relationship between knowledge and attitudes regarding SADARI among 10th-grade female students at MAN (State Islamic Senior High School) 3 Sleman. This study employed a quantitative correlational approach with a cross-sectional design, involving a sample of 66 respondents. Data were collected using a questionnaire containing questions related to BSE. The Spearman Rank test showed a p-value of 0.606, which is greater than 0.05 (p > 0.05). This indicates that there is no significant relationship between the level of knowledge and attitudes toward BSE among 10th-grade female students at MAN 3 Sleman. In addition, the correlation coefficient (r) was 0.065, indicating a very weak relationship between knowledge and attitudes. There is no significant relationship between knowledge and attitudes regarding BSE among 10th-grade female students at MAN 3 Sleman. Schools and healthcare providers are encouraged to enhance structured and continuous BSE education and incorporate educational media during health counseling to foster positive attitudes.
Hubungan Faktor Sosial Ekonomi dan Proses Pengambilan Keputusan dengan Praktik Pemberian MPASI oleh Ibu Berdasarkan Teori Perilaku Konsumen di Wilayah Kerja Puskesmas Putat Jaya
Inappropriate complementary feeding (MPASI) practices remain a public health concern, particularly during the first 1,000 days of life, as they contribute to the risk of growth disorders such as stunting. This study aimed to analyze the relationship between socioeconomic factors and maternal decision-making processes with complementary feeding practices based on consumer behavior theory. This study employed an observational analytic design with a cross-sectional approach involving 240 mothers with children aged 6–23 months in the working area of Puskesmas Putat Jaya, Surabaya. Data were collected through structured interviews and analyzed using the Chi-Square test. The results showed significant relationships between socioeconomic status and decision-making processes, as well as between decision-making processes and complementary feeding practices (p<0.05). Mothers with higher socioeconomic status tended to have better decision-making processes and more appropriate feeding practices. However, overall practices were not fully aligned with recommended standards. These findings indicate that improving complementary feeding practices requires not only knowledge enhancement but also strengthening maternal decision-making capacity within their socioeconomic context.
Hubungan Kafein dan Durasi Tidur Terhadap VO2Max pada Siswa Sekolah Sepak Bola Surabaya
This study aims to analyze the relationship between caffeine consumption and sleep duration on VO₂Max levels among soccer school (SSB) students in Surabaya. VO₂Max is a key indicator of cardiorespiratory fitness and athletic performance. This research employed a quantitative cross-sectional design with an analytical observational approach. A total of 162 SSB students were included as research participants from several soccer schools in Surabaya. Data were collected using the Food Frequency Questionnaire (FFQ) to assess caffeine intake and the Pittsburgh Sleep Quality Index (PSQI) to evaluate sleep duration, and were analyzed using the Chi-Square test. The results revealed a significant relationship between caffeine consumption and sleep duration with VO₂Max (p<0.001). Students with higher caffeine consumption (≥3.5) and adequate sleep duration (≥7 hours) tended to have better VO₂Max values compared to those with lower caffeine intake and insufficient sleep. These findings indicate that appropriate caffeine consumption and adequate sleep duration play an important role in improving cardiorespiratory fitness. Therefore, proper education on healthy lifestyle habits is essential to optimize the performance of young athletes.
Literature Review: Hubungan Preferensi Makanan dan Pengetahuan Food Waste dengan Perilaku Food Waste
Food waste is a global issue that has a major impact on the economy, environment, and food security. The high rate of food waste is directly influenced by food waste behavior. Also, food waste behavior does not just appear, but it is supported by other factors such as food waste knowledge and food preferences. As an effort to prevent the increase in food waste, it is important to know the relationship between these two factors and the occurrence of food waste behavior. The method used is a literature review of open access scientific articles with English language used and published in the period 2015–2025 through the Google Scholar databases. The results of the review show that most studies found a significant relationship between food waste knowledge and food preferences with food waste behavior. However, some studies also showed inconsistent results. Although many studies support the relationship between food waste knowledge and food preferences with food waste behavior, the difference in results also indicates that there are still other factors that are strongly related to food waste behavior, so more comprehensive efforts are needed to reduce the occurrence of food waste behavior.
Efektivitas Kompres Dingin (Cryotherapy) terhadap Penurunan Nyeri pada Pasien Fraktur Humerus Dextra Post ORIF
Fracture is a condition characterized by the disruption of bone continuity that often causes acute pain, especially in patients following Open Reduction and Internal Fixation (ORIF). Effective pain management is essential to support the recovery process and improve patient comfort during hospitalization. This study aimed to determine the effectiveness of cold compress therapy (cryotherapy) in reducing pain intensity in post-ORIF patients. This study used a case study method on a patient diagnosed with a right humerus fracture at PKU Muhammadiyah Bantul Hospital. Data were collected through interviews, interventions, and documentation using the PQRST method. Cryotherapy was administered once daily for three consecutive days using an ice bag applied to the painful area. The results showed a gradual decrease in pain intensity from scale 7 to 6 on the first day, 5 on the second day, and 4 on the third day. The patient also reported increased comfort after the intervention. These findings indicate that cryotherapy is effective as a non-pharmacological intervention in reducing postoperative pain and improving patient comfort.
Efektivitas Kinesio Taping terhadap Nilai Neck Disability Index pada Myofascial Pain Syndrome Otot Upper Trapezius: A Systematic Literature Review
Myofascial pain syndrome (MPS) in the upper trapezius muscle is one of the disorders commonly found in the neck area, characterized by myofascial trigger points (MTrP) in taut bands or tight muscle bands. Kinesio taping (KT) is a non-invasive therapy used in the management of MPS of the upper trapezius to improve neck disability measured using the Neck Disability Index (NDI). However, stronger evidence is still needed regarding the effectiveness of KT in reducing neck disability scores in MPS upper trapezius. This study aims to review and analyze the effectiveness of KT on NDI scores in MPS upper trapezius. The research method used is a systematic review employing PRISMA-P and the PICOS framework. The sample and population of the study consist of articles obtained from databases such as Crossref, Scopus, PubMed, Google Scholar, and Semantic Scholar. Keywords such as "Kinesio Taping," "Myofascial Pain Syndrome," and "Myofascial Trigger Point" were used. The results of the descriptive analysis of the selected articles showed that KT significantly reduced the NDI value in MPS upper trapezius. In conclusion, KT is effective in improving functional disability in the neck caused by MPS upper trapezius, and KT can be a therapeutic option either alone or in combination with other therapies.
Pengaruh Fasilitas Kesehatan dan Kinerja terhadap Kepuasan Pasien melalui Kualitas Pelayanan di Ruang Kebidanan RS.Cut Meutia Medika Nusantara Kota Langsa
Healthcare is an integral part of health development in Indonesia, which aims to optimally improve public health. Hospitals, as healthcare facilities, are required to provide quality, safe, and patient-centered services. Service quality is a key indicator of service success, as good service impacts patient satisfaction. One of the most important services in hospitals is obstetrics, which directly relates to maternal and infant health, making patient satisfaction a crucial aspect. Midwives, as professional healthcare workers, play a strategic role in providing comprehensive, sustainable, and patient-centered midwifery care. This study aims to analyze the influence of healthcare facilities and midwife performance on patient satisfaction through service quality. The method used is a quantitative study with an analytical approach and a cross-sectional design. The results of the multiple linear regression test indicate that midwife performance has a more dominant influence on service quality than healthcare facilities. Meanwhile, regarding patient satisfaction, service quality is the most dominant factor, followed by midwife performance and healthcare facilities. The conclusion of this study is that service quality reflects the overall patient experience and is a key factor in improving patient satisfaction.
Literature Review: Hubungan Stres dan Asupan Gizi terhadap Dismenore Primer pada Remaja Perempuan
Primary dysmenorrhea is a common reproductive health problem among adolescents and women of reproductive age, significantly affecting quality of life and academic productivity. Psychological stress and dietary patterns are considered important contributing factors influencing the incidence and severity of menstrual pain. This study aimed to analyze the relationship between stress levels and dietary intake with the occurrence of primary dysmenorrhea in adolescents and women of reproductive age. A literature review was conducted using articles published between 2015 and 2025 retrieved from Scopus, PubMed, and Google Scholar. Studies meeting the inclusion criteria were analyzed descriptively and narratively. The findings showed that the prevalence of primary dysmenorrhea ranged from 54.4% to 90.6%. Higher stress levels were significantly associated with increased risk and intensity of menstrual pain (OR up to 4.03). Frequent consumption of sugary foods, fast food, and pro-inflammatory dietary patterns was linked to higher incidence and severity of dysmenorrhea (OR up to 4.8), whereas adequate intake of fruits, vegetables, iron, calcium, and magnesium demonstrated protective effects. Primary dysmenorrhea is multifactorial and significantly associated with stress and dietary intake; therefore, integrated stress management and nutritional education interventions are recommended in adolescent reproductive health programs.
Pengaruh Pemberian Kompres Hangat terhadap Penurunan Intensitas Nyeri pada Pasien Gastritis: Studi Kasus
Gastritis is an inflammation of the gastric mucosa that often causes pain in the epigastric area, which can reduce patient comfort and quality of life. This condition requires treatment that is not only pharmacological, but can also be supported by non-pharmacological interventions such as warm compresses that function to provide a relaxing effect and improve blood circulation. This study aims to determine the effect of warm compresses on reducing pain intensity in gastritis patients. The research method used was descriptive with a case study approach on one patient treated in the inpatient ward. Data collection was carried out through interviews, observation, and documentation using the PQRST method to assess pain. The intervention in the form of warm compresses was given for three days with a frequency of once a day for ± 15–20 minutes in the epigastric area. The results showed a gradual decrease in pain intensity from a scale of 6 to a scale of 2 after the intervention, as well as an increase in patient comfort. The implications of this study indicate that warm compresses can be used as an effective, safe, and easy-to-implement independent nursing intervention to help reduce pain in gastritis patients and improve the quality of nursing care.
Association between Dietary Omega-3 Intake and Dry Eye Syndrome in Adults: A Cross-Sectional Study
Dry eye syndrome (DES) is a common ocular surface disorder that can impair visual function and quality of life, particularly among working-age adults. Although DES has a multifactorial etiology, nutritional factors, such as omega-3 fatty acid intake, have been suggested to modulate inflammation associated with the condition. This study aimed to investigate the association between dietary omega-3 intake and dry eye syndrome in adults. This cross-sectional analytical observational study included 88 participants aged 15-59 years. Participants were selected using consecutive non-random sampling and assessed with a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) to estimate omega-3 intake, while dry eye symptoms were evaluated using the Ocular Surface Disease Index (OSDI). Statistical analyses included chi-square and Fisher’s exact test. The results showed that 51.1% of the participants had insufficient omega-3 intake (<250 mg/day), and 29.5% experienced dry eye syndrome. No statistically significant association was found between sex or age and DES occurrence. However, a significant association was found between omega-3 intake and dry eye syndrome (p < 0.001), with individuals consuming insufficient omega-3 having a substantially higher risk of developing DES. These findings suggest that adequate omega-3 intake may play a protective role in dry eye syndrome. This study underscores the potential of dietary interventions as a strategy for preventing and managing DES.
Copyright (c) 2026 Anisa Henintya Rizki Putri, Husnun Amalia https://creativecommons.org/licenses/by-sa/4.0
Efektivitas Edukasi menggunakan Video terhadap Peningkatan Pengetahuan dan Keterampilan Sadari pada Siswi Kelas XI di MAN 2 Yogyakarta
Breast cancer is a serious health problem among women, with incidence and mortality rates that continue to rise. The disease is often detected at an advanced stage due to low levels of awareness, knowledge, and skills related to early detection. Among adolescent girls, particularly high school students, knowledge and skills regarding Breast Self-Examination (BSE) remain limited. This is largely due to restricted access to health information, a lack of targeted educational initiatives, and learning methods that are insufficiently engaging. BSE is a simple and effective early detection method that can be performed independently beginning in adolescence. Video-based education is considered an effective tool for enhancing adolescents’ understanding. This study aims to determine the effectiveness of video-based education in improving knowledge and BSE skills among Grade XI female students at MAN (State Islamic Senior High School) 2 Yogyakarta. This study employed a pre-experimental design using a one-group pre-test and post-test approach. The study population consisted of all Grade XI female students at MAN 2 Yogyakarta, with a sample of 59 students selected through purposive sampling on predetermined inclusion criteria. The intervention involved a single session of a BSE educational video lasting approximately seven minutes. It was conducted in 15 groups, with each group accompanied by one facilitator. Data were analyzed using the nonparametric Wilcoxon statistical test. The Wilcoxon test results showed a p-value of 0.000 (p < 0.05) for both knowledge and skills variables, indicating a statistically significant improvement between the pre-test and post-test scores. In conclusion, video-based education was proven effective in improving knowledge and BSE skills among Grade XI female students at MAN 2 Yogyakarta. Future researchers are encouraged to assess BSE skills using a structured checklist based on standardized evaluation criteria.
Copyright (c) 2026 Inayah Rosmayanti, Sri Lestari https://creativecommons.org/licenses/by-sa/4.0
Literature Review: Analisis Target Molekuler Dan Pendekatan Kimia Medisinal Dalam Pengembangan Terapi Kanker Servik
Cervical cancer is one of the most common cancers worldwide and is largely caused by Human Papillomavirus (HPV) infection, particularly types 16 and 18. The development of this cancer is influenced by the E6 and E7 oncoproteins, which disrupt the function of p53 and Rb proteins, as well as the involvement of cellular signaling pathways such as PI3K/AKT/mTOR and EGFR. Limitations of conventional therapies, such as resistance and side effects, drive the need for more targeted and selective therapeutic agents. This study aims to analyze the main molecular targets of cervical cancer and the medicinal chemistry approaches used in its therapeutic development. The method involved a review of 12 open access articles using molecular docking, molecular dynamics, QSAR, and network pharmacology approaches. The findings identified two main target groups: viral targets comprising the HPV E6 and E7 oncoproteins, and cellular targets including the PI3K/AKT/mTOR pathway, EGFR, PARP1, CDK1, and VEGFR. Various medicinal chemistry strategies, from structure-based and ligand-based drug design to multi-target network pharmacology approaches, proved effective in identifying potential inhibitor candidates. Bioactive compounds such as quercetin, gossypol, bixin, and rutin demonstrated stable interactions with these targets. However, further experimental validation is needed to support the development of clinically effective and safe therapies.
Copyright (c) 2026 Saeful Amin, Aliya Fayyaza Khairun Nisa, Shilvia Siti Nurohmah, Salla Sabillah https://creativecommons.org/licenses/by-sa/4.0
Perubahan Pengetahuan, Pola Konsumsi, Asupan Gizi, dan Food acculturation Mahasiswa Baru Perantau dan Nonrantau: Penelitian Kohort 5 Bulan
This study examines changes in nutritional knowledge, dietary patterns, nutrient intake, and food acculturation among first-year migrant and non-migrant students. A 5 months prospective cohort design was employed involving 32 students from the Faculty of Public Health, Universitas Airlangga. Students were randomly divided equally into migrant and non-migrant groups. Data were collected using questionnaires, food frequency questionnaires, 3×24-hour food recall, and analyzed using descriptive and inferential statistics. The findings indicated no significant differences or changes in nutritional knowledge between groups throughout the observation period (p > 0.05). However, dietary patterns varied, with migrant students showing increased consumption of practical and fast foods. Nutrient intake, particularly energy and protein, was initially lower among migrant students but improved significantly over time, reflecting adaptation to a new environment. Food acculturation was evident among migrant students, with a significant increase in scores during the study period (p = 0.007), indicating gradual adjustment to local eating habits. These results highlight the influence of environmental adaptation on students’ dietary behavior and emphasize the need for targeted nutrition interventions to promote healthy eating habits during the early university transition.
Copyright (c) 2026 Amany Ges Anuz, Trias Mahmudiono https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Diet Gluten-Free Casein-Free (GFCF) terhadap Gejala Perilaku pada Anak dengan Autism Spectrum Disorder (ASD): Literature Review
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, communication difficulties, and restricted and repetitive behaviors. In addition to these core symptoms, children with ASD often experience gastrointestinal disturbances that are thought to be related to the gut–brain axis. One non-pharmacological intervention that has been widely studied to reduce ASD symptoms is the gluten-free casein-free (GFCF) diet. However, evidence regarding its effectiveness in improving behavioral symptoms remains inconsistent. This study aims to review previous research on the impact of gluten and casein consumption on behavioral symptoms in children with ASD using a narrative literature review approach. Literature searches were conducted in PubMed, ScienceDirect, and Google Scholar for articles published between 2014 and 2024 using the keywords Autism Spectrum Disorder (ASD), behavior, GFCF diet, gluten, and casein. The review results indicate that most studies report potential benefits of the GFCF diet in improving certain behavioral symptoms in children with ASD, particularly hyperactivity, behavioral problems, stereotypical behavior, attention, and cognitive function. Some studies also show improvements in autism evaluation scores after dietary implementation over a specific period. However, findings remain inconsistent due to differences in study design, sample size, intervention duration, dietary adherence, and the heterogeneity of ASD characteristics among children. In conclusion, the GFCF diet has potential as a complementary intervention to improve certain behavioral symptoms in children with ASD, but further high-quality studies with larger samples are needed to confirm its effectiveness more consistently.
Copyright (c) 2026 Rayna Rosellini, Edwin Rasendriya https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Relaksasi Otot Progresif terhadap Kualitas Tidur pada Lansia
Old age is the final phase in the human life cycle, characterised by a decline in physiological function. Global data shows that the prevalence of old age will increase from 33.69 million to 48.19 million by 2035. One of the effects of this decline in physiological function is a disruption in the quality of sleep among the elderly. As many as 50-60% of elderly people in Indonesia experience sleep disorders. One way to overcome sleep disorders is through relaxation therapy. Progressive Muscle Relaxation is a technique performed by stretching and relaxing certain muscles to relax the body. The purpose of this study was to determine the effectiveness of progressive muscle relaxation on the quality of sleep in elderly people. This research method involved a nursing care process from assessment to evaluation using a case study design. The research sample consisted of one elderly person with moderate sleep quality. The intervention was given for 10-15 minutes using eight movements with a frequency of twice a week for one month. The data were analysed using pre-test and post-test PSQI questionnaires to determine sleep quality. The results of this study indicate that progressive muscle relaxation training has an effect on improving sleep quality in the elderly.
Copyright (c) 2026 Lucia Arum Sari, Dinasti Pudang Binoriang https://creativecommons.org/licenses/by-sa/4.0
Hubungan Antara Kualitas Diet dengan Status Gizi pada Siswa SMAN 9 Surabaya
This study was conducted in response to the increasingly complex nutritional issues among adolescents, reflected in the coexistence of undernutrition and overnutrition within the same population, which are closely associated with dietary consumption patterns. The research aimed to investigate the relationship between diet quality and the nutritional status of students at SMAN 9 Surabaya. A quantitative approach with a cross-sectional design was employed, involving 85 participants selected based on the estimated sample requirement for correlation analysis. Dietary intake data were collected using two non-consecutive 24-hour food recalls and subsequently assessed using the Diet Quality Index for Adolescents (DQI-A). Nutritional status was determined through BMI-for-age calculations in accordance with the World Health Organization standards. Data analysis was performed using correlational testing and Chi-Square analysis to identify differences in proportions. The findings revealed that the respondents’ diet quality remained suboptimal, while most students were categorized as having normal nutritional status, although cases of undernutrition and overnutrition were still identified. A significant association was found between diet quality and nutritional status (p = 0.001), indicating that better diet quality tended to be linked with normal nutritional status. Based on the DQI-A components, dietary quality demonstrated a significant relationship with nutritional status (p = 0.007), whereas dietary diversity (p = 0.597) and dietary equilibrium (p = 0.507) showed no significant associations. These findings highlight that diet quality, particularly food selection patterns, plays an important role in determining adolescent nutritional status. Therefore, improving nutritional conditions requires more intensive nutrition education interventions focusing on healthy food choices, increased fruit and vegetable consumption, and controlled intake of sugar, salt, and fat, supported consistently by both individuals and the school environment.
Copyright (c) 2026 Ussy Nastiti, Triska Susila Nindya https://creativecommons.org/licenses/by-sa/4.0
Hubungan antara Pengaruh Teman Sebaya, Kebiasaan Makan di Luar (Eating Out), dan Pola Konsumsi Fast Food dengan Status Gizi Lebih Remaja di SMAN 1 Surabaya
Adolescents are considered a vulnerable group to nutritional problems because they experience rapid physical growth accompanied by lifestyle changes and unhealthy eating habits. The increasing prevalence of overweight and obesity among teenagers has become a major public health concern that requires serious attention. This study was conducted to examine the relationship between peer influence, the frequency of eating out, and fast-food consumption habits with the incidence of overweight among students at SMAN 1 Surabaya. The research applied a quantitative approach using an analytical observational design with a cross-sectional method. A total of 81 students participated in the study and were selected through proportional random sampling. Data were collected using questionnaires, SQ-FFQ forms, and anthropometric measurements, then analyzed using the Chi-Square statistical test. The findings revealed significant associations between peer influence, eating out frequency, and fast-food consumption habits with the occurrence of overweight among adolescents. Students who more frequently consumed meals outside the home and regularly ate fast food showed a greater tendency to experience overweight and obesity. These results indicate that social environments and modern dietary patterns contribute to the increasing prevalence of overweight among adolescents. Therefore, nutrition education and healthy lifestyle promotion should be strengthened through the involvement of schools, families, and peer groups.
Copyright (c) 2026 Janice Fiona Putri, Dini Ririn Andrias https://creativecommons.org/licenses/by-sa/4.0
Invisible Threat: Kajian Literatur tentang Paparan Mikroplastik dan Implikasinya terhadap Kesehatan Manusia
Microplastics are extremely small plastic particles that have become a major concern in public health and environmental studies. This literature review aims to discuss the sources of microplastics, their routes of exposure to the human body, their distribution in organs, and their potential health impacts. The method used was a literature review of scientific articles and reports published from 2021 onward, retrieved from Google Scholar, PubMed, ScienceDirect, and official websites of organizations such as the WHO, OECD, and the World Bank. The review findings show that microplastics originate from plastic waste, synthetic clothing, cosmetics, vehicle tires, and food packaging. These particles have been detected in blood, lungs, the placenta, feces, and various human tissues, indicating that human exposure is widespread. However, evidence from human studies is still limited, so cause-and-effect relationships cannot yet be confirmed with certainty. Based on these findings, further research is needed to better understand the long-term health effects of microplastics. In addition, efforts to reduce single-use plastics, improve waste management systems, and increase public education are essential to reduce exposure and prevent future health risks.
Copyright (c) 2026 Rabiatul Adawiyah, Rizky Alviansyah, Khusnun Nadiah, Muhammad Yunus, Dianna Ratnawati https://creativecommons.org/licenses/by-sa/4.0
Hubungan Self-Compassion dengan Self-Objectification pada Mahasiswi Pengguna Tiktok di Kota Jambi
This study aims to analyze the relationship between self-compassion and self-objectification among female TikTok users in Jambi City. The study used a quantitative correlational approach with a cross-sectional design. A total of 218 female students in Jambi City aged 18–25 years who actively use TikTok were selected using a purposive sampling technique. The instruments used were the Self-Compassion Scale (SCS) adapted into Indonesian (Skala Welas Diri) and the Objectified Body Consciousness Scale (OBCS). Data analysis used the Pearson Product Moment correlation test. The results showed a significant negative relationship between self-compassion and self-objectification (r = -0.216; p = 0.001). The higher the self-compassion, the lower the tendency for self-objectification. The majority of respondents had moderate to high levels of self-compassion, while self-objectification was in the moderate category. The duration of TikTok use of more than 2 hours per day was associated with a higher tendency for self-objectification. These findings confirm the role of self-compassion as a protective factor against self-objectification in the context of visual-based social media use.
Copyright (c) 2026 Salsabila Raina Fazra, Rion Nofrianda, Ayu Ulivia https://creativecommons.org/licenses/by-sa/4.0
Tinjauan Kimia Medisinal: Hubungan Struktur-Aktivitas Senyawa Bahan Alam sebagai Kandidat Antikanker Payudara
Breast cancer remains a major global health challenge, with treatment effectiveness often limited by drug resistance and the toxic side effects of chemotherapy on normal cells. The exploration of bioactive compounds from natural sources through a medicinal chemistry approach offers a promising alternative strategy. This study aims to examine the molecular mechanisms of action and Structure-Activity Relationships (SAR) of various natural compound scaffolds as potential breast anticancer agents. The method employed was a systematic narrative literature review of 15 recent scientific articles evaluating computational parameters, including molecular docking, as well as in vitro and in vivo activities. The results indicate that polyphenols, flavonoids such as quercetin and EGCG, and curcumin possess strong cytotoxic activity and high binding affinity toward cancer-related target macromolecules. SAR analysis demonstrates that key structural features, including the number and position of free phenolic hydroxyl groups, the presence of gallate ester groups, and conjugated diketone systems, play a crucial role in determining ligand receptor complex stability. These interactions are supported by hydrogen bonding, hydrophobic interactions, and favorable steric compatibility within receptor binding sites. Computational findings further suggest that structural optimization can enhance ligand selectivity and improve pharmacokinetic properties. This study concludes that natural phytochemical scaffolds have significant potential as lead compounds and provide a rational basis for Computer-Aided Drug Design in developing more potent, selective, multi-target, and safer breast anticancer therapies.
Copyright (c) 2026 Saeful Amin, Icha Aisah Azzahra, Natasya Zakiatul Awalia Irhan, Syifa Alifia Azzahra https://creativecommons.org/licenses/by-sa/4.0
The Combined Role of Immunotherapy and Radiotherapy in Muscle-Invasive Bladder Cancer: A Systematic Review
Muscle-invasive bladder cancer (MIBC) is an aggressive malignancy associated with high morbidity, reduced survival, and impaired quality of life. Radiotherapy (RT) has been widely used as a bladder-preserving strategy, particularly for patients unsuitable for surgery or systemic chemotherapy. RT may also enhance tumor immunogenicity through programmed death-ligand 1 (PD-L1) upregulation, providing a rationale for combination therapy with immunotherapy. This study aimed to evaluate the effectiveness of combining immunotherapy and radiotherapy in MIBC treatment. A systematic review was conducted following PRISMA 2020 guidelines using the PICO framework. Literature searches were performed in PubMed, Embase, Cochrane, ClinicalTrials.gov, Web of Science, and Scopus databases for studies published between 2016 and 2025. Risk of bias was assessed using the Cochrane Risk of Bias Tool and ROBINS-I. Of 105 identified studies, five met the inclusion criteria and were included in the final analysis. Only one Phase II randomized controlled trial demonstrated low risk of bias in randomization and allocation concealment. ROBINS-I assessment indicated moderate to serious risk in confounding and participant selection domains. Clinical findings showed promising outcomes, with complete response rates ranging from 35%–50% and partial response rates from 25%–40%. Median overall survival ranged from 24–30 months, with favorable disease-free and progression-free survival outcomes. Combined immunotherapy and radiotherapy demonstrate potential to improve survival and disease control in MIBC; however, further rigorous clinical studies are needed to optimize patient-centered treatment strategies.
Copyright (c) 2026 Aristya Ika Wardani https://creativecommons.org/licenses/by-sa/4.0
Inovasi Zea Coffee Tab Berbasis Robusta dan Rambut Jagung sebagai Minuman Fungsional untuk Remaja Overweight
Nutritional problems among adolescents are increasingly associated with unhealthy dietary habits and low physical activity, contributing to the rising prevalence of overweight. According to the 2023 Indonesian Health Survey, overweight prevalence among adolescents ranges from 12% to 16.2%. This study aimed to develop Zea Coffee Tab, a functional beverage made from Robusta coffee and corn silk containing bioactive compounds, including caffeine and flavonoids, which may support metabolism and body fat oxidation. An experimental method with a Completely Randomized Design (CRD) was employed. The evaluated parameters included organoleptic tests (hedonic and hedonic quality) involving 30 semi-trained panelists, proximate analysis, and identification of bioactive compounds. Data were analyzed using the Kruskal–Wallis, Mann–Whitney, One-Way ANOVA, and Duncan’s multiple range tests. Three formulations were tested: F1 (30% Robusta coffee:70% corn silk), F2 (50%:50%), and F3 (70%:30%). The findings showed that F3 was the most preferred formulation, with an acceptance score categorized as “very much liked.” The product contained energy ranging from 319.20–324.26 kcal/100 g, protein 5.12–5.34%, fat 0.48–0.58%, carbohydrates 73.85–74.51%, moisture 9.12–9.66%, ash 2.10–2.32%, caffeine 182.45–205.86 mg/100 g, and flavonoids 4.28–6.03 mg/100 g. Zea Coffee Tab has the potential to serve as a healthy functional beverage for overweight adolescents. Further studies on shelf life and clinical effectiveness are recommended to support product commercialization.
Copyright (c) 2026 Intan Afita Khoirun Nisa, Efina Amanda, Mulya Agustina https://creativecommons.org/licenses/by-sa/4.0
Hubungan Pola Konsumsi Junk-Food dengan Perilaku Beresiko Penyakit Tidak Menular Pada Remaja SMP Terpadu Al-Farabi
Junk food is generally high in calories, sugar, salt, and fat but low in fiber, vitamins, and minerals. Excessive junk food consumption among adolescents is a risk factor for the increasing incidence of non-communicable diseases (NCDs), such as obesity, hypertension, diabetes mellitus, and cardiovascular disease. Adolescence is a crucial period in the formation of eating habits that will influence health status in adulthood. Lifestyle changes, technological developments, and exposure to fast food advertisements on social media also influence adolescents' consumption behavior.This study aims to determine the relationship between junk food consumption patterns and risk behaviors for non-communicable diseases among students at Alfarabi Integrated Junior High School. The study used a descriptive quantitative approach with a cross-sectional design. Data collection was conducted on May 23, 2026, by distributing questionnaires directly to 34 ninth-grade students after receiving education about junk food and its impact on health. The results showed that 38.2% of respondents consumed junk food 1–2 times per week, 38.2% consumed it 3–5 times per week, and 23.5% consumed junk food every day. The most commonly consumed types of junk food were fast food (41.2%), instant noodles (32.4%), and sugary drinks (17.6%). Most respondents (70.6%) only exercised occasionally. Frequent health complaints included fatigue, acne, and weight gain. This study shows that high junk food consumption combined with low physical activity can be a risky behavior that contributes to increased risk factors for non-communicable diseases in adolescents. Therefore, education and the promotion of healthy lifestyle habits from school age are necessary.
Copyright (c) 2026 Irfan Sazali Nasution, Annisa Zulliani, Chairika Romadani, Cindy Sipahutar, Dwinayla Astri, Intan Lestari, Nadra Daulay https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Senam Menopause terhadap Kualitas Tidur Wanita Perimenopause di PMB Rama Agustina
Sleep disturbance is one of the most common complaints experienced by perimenopausal women due to hormonal changes. Menopause exercise is a complementary therapy that may help improve sleep quality through regular physical activity. Objective: To determine the effect of menopause exercise on sleep quality among perimenopausal women at PMB Rama Agustina. Methods: This study employed a quasi-experimental design with a one-group pretest-posttest approach. A total of 30 perimenopausal women were selected using purposive sampling. Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI). The intervention consisted of menopause exercise conducted for four weeks. Data were analyzed using the Wilcoxon Signed Rank Test. Results: The mean sleep quality score decreased from 10.23 before the intervention to 6.37 after the intervention, with a mean difference of 3.86 points. The Wilcoxon test showed a p-value of 0.000 (p<0.05). Conclusion: Menopause exercise had a significant effect on improving sleep quality among perimenopausal women at PMB Rama Agustina.
Copyright (c) 2026 Novi Rida Eriyani https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Pendidikan Kesehatan Terhadap Tingkat Pengetahuan dan Sikap Siswi dalam Penanganan Dismenorea di SMP Negeri 1 Mlati
Adolescence is a transitional period from childhood to adulthood, typically characterized by puberty between the ages of 12 and 14 years, accompanied by physical, social, and emotional changes. In adolescent girls, reproductive maturation is marked by the onset of menstruation as an early indicator of maturity, which is often accompanied by menstrual disorders such as dysmenorrhea. Dysmenorrhea, or menstrual pain, is a common condition among adolescent girls and may interfere with academic activities and overall quality of life. Inadequate knowledge and inappropriate attitudes toward its management often lead adolescents to neglect symptoms or adopt suboptimal pain management strategies. This study aims to examine the effect of health education on female students’ knowledge and attitudes regarding dysmenorrhea management at SMP Negeri (State Junior High School) 1 Mlati. A pre-experimental study with a one-group pretest-posttest design was employed. The study population consisted of all eighth-grade female students, with a sample of 66 participants selected through purposive sampling based on the inclusion criteria of having experienced menarche and being willing to participate throughout the study. Data were analyzed using the Wilcoxon nonparametric statistical test to assess differences before and after the health education intervention. The results of the Wilcoxon test demonstrated a significant improvement in both knowledge (p = 0.000) and attitudes (p = 0.002) following the intervention. It can be concluded that health education has a significant effect on improving female students’ knowledge and attitudes toward dysmenorrhea management. Future researchers are encouraged to develop more innovative educational media by utilizing social media platforms such as Instagram and TikTok to enhance the effectiveness and attractiveness of educational interventions.
Copyright (c) 2026 Fidya Tri Prananti, Sri Lestari https://creativecommons.org/licenses/by-sa/4.0
Hubungan Pengetahuan Gizi, Eating Behavior, dan Asupan Ultra Processed Foods dengan Status Gizi Pelajar SMA Muhammadiyah 2 Surabaya
Nutritional problems among adolescents remain a public health concern in Indonesia due to their association with an increased risk of non-communicable diseases later in life. Changes in dietary patterns characterized by increased consumption of ultra-processed foods (UPFs), unhealthy eating behaviors, and inadequate nutritional knowledge are considered important factors influencing adolescents' nutritional status. This study aimed to analyze the relationship between nutritional knowledge, eating behavior, and ultra-processed food intake with the nutritional status students at SMA Muhammadiyah 2 Surabaya. This study employed an analytical observational design with a crosssectional approach. Participants were selected using proportional random sampling. Nutritional knowledge was assessed using a nutrition knowledge questionnaire, eating behavior was measured using the Dutch Eating Behavior Questionnaire (DEBQ), and ultra-processed food intake was collected using Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ). Nutritional status was determined using Body Mass Index-for-Age (BMI-for-Age). Data were analyzed using the ChiSquare test with a significance level of α=0.05. The results showed no significant association between nutritional knowledge and nutritional status (p=0.113), external eating and nutritional status (p=0.142), energy intake from UPFs and nutritional status (p=0,522), or fat intake from UPFs and nutritional status (p=0,136). However, significant associations were found between emotional eating and nutritional status (p=0.023), well as restrained eating and nutritional status (p=0.012). This study concludes that eating behavior dimensions, particularly emotional eating and restrained eating, are associated with the nutritional status of students at SMA Muhammadiyah 2 Surabaya. Therefore, efforts to promote healthy eating behaviors and improve self-regulation in managing dietary habits among adolescents are needed.
Copyright (c) 2026 Alyssia Anindia Putri Nayla Sekarhati https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Herbal Therapy Compress Ball terhadap Nyeri Punggung Bawah dan Kecemasan pada Ibu Hamil Trimester III
Background: Back pain and anxiety are common complaints experienced by third-trimester pregnant women due to physiological, biomechanical, and psychological changes during pregnancy. One complementary therapy that can be used to address these complaints is the Herbal Therapy Compress Ball, a warm compress therapy combined with herbal ingredients to provide relaxation and pain-relieving effects. Objective: To determine the effect of Herbal Therapy Compress Ball on back pain and anxiety among third-trimester pregnant women. Methods: This study employed a pre-experimental design with a one-group pretest-posttest approach. The sample consisted of 32 third-trimester pregnant women selected using a purposive sampling technique. Research instruments included the Numeric Rating Scale (NRS) to assess back pain and the Hamilton Anxiety Rating Scale (HARS) to measure anxiety levels. Data were collected before and after the administration of Herbal Therapy Compress Ball and analyzed using the Wilcoxon Signed Rank Test with a significance level of α = 0.05. Results: The findings showed a reduction in both back pain and anxiety levels following the administration of Herbal Therapy Compress Ball. Statistical analysis using the Wilcoxon Signed Rank Test yielded a p-value of 0.004 (p < 0.05), indicating a significant effect of Herbal Therapy Compress Ball on reducing back pain and anxiety among third-trimester pregnant women. Conclusion: Herbal Therapy Compress Ball was effective in reducing back pain and anxiety among third-trimester pregnant women. This therapy can be considered a safe and easily applicable non-pharmacological complementary intervention in midwifery care.
Copyright (c) 2026 Deby Meitia Sandy, Illustri Illustri https://creativecommons.org/licenses/by-sa/4.0
Faktor Risiko Malnutrisi pada Lansia: Tinjauan Sistematis Tentang Anoreksia dan Polifarmasi
Malnutrition in older adults was recognized as a common health problem associated with increased morbidity, mortality, physical decline, and reduced quality of life. This condition was influenced by various factors, particularly geriatric anorexia and polypharmacy, which were frequently found among the elderly population. This study aimed to analyze the risk factors of malnutrition in older adults with a focus on anorexia and polypharmacy using a PRISMA-based systematic literature review method. Articles were collected from Google Scholar, PubMed, ScienceDirect, and NCBI databases published between 2020-2026. A total of 20 national and international articles that met the inclusion criteria were analyzed descriptively and thematically. The findings showed that geriatric anorexia became a dominant factor contributing to inadequate energy and protein intake due to decreased appetite, chewing difficulties, tooth loss, xerostomia, and early satiety. Polypharmacy also contributed to malnutrition through medication side effects such as nausea, taste disturbances, and appetite loss. Other contributing factors included depression, chronic diseases, physical limitations, and socioeconomic conditions that worsened the nutritional status of older adults. Management of malnutrition in the elderly required a multidisciplinary approach through routine nutritional screening, medication monitoring, nutrition education, and family support to improve the quality of life of older adults.
Copyright (c) 2026 Najwa Pramesthi Setyaputri, Farapti Farapti https://creativecommons.org/licenses/by-sa/4.0
Hubungan Frekuensi Konsumsi Lemak, Tingkat Pemenuhan Asupan Lemak, dan Kualitas Tidur dengan Kejadian Gastritis pada Mahasiswi Gizi Angkatan 2023-2024 UNESA
Gastritis incidence is relatively high in East Java, reaching 44.5%. Gastritis, condition characterized by chronic or acute inflammation of stomach lining, and common among productive age, including female students. Gastritis influenced by dietary habits and daily sleep quality. This study to determine the relationship between frequency fat consumption, level fat intake fulfillment, and sleep quality with gastritis incidence in Female Nutrition Students of 2023-2024 Class UNESA. This study used a quantitative cross-sectional design, and data collected using purposive sampling. Respondent’s study were 92 Female Nutrition Students from 2023-2024 Class UNESA. Frequency fat consumption and level fat intake fulfillment collected by Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) interviews, sleep quality collected by Pittsburgh Sleep Quality Index (PSQI) questionnaire, and gastritis incidence collected from medical history based on a doctor’s diagnosis. The data were analyzed using Chi-Square test. The results showed that there was no relationship between frequency fat consumption (p-value=0.254) and level fat intake fulfillment (p-value=0.295) with incidence of gastritis, however, there was a relationship between sleep quality (p-value=0.010) and incidence of gastritis in Female Nutrition Students of 2023–2024 Class UNESA. Therefore, Female Nutrition Students of 2023-2024 Class UNESA are advised to improve sleep quality to reduce their risk of gastritis.
Copyright (c) 2026 Evelyna Clarissa Adristi https://creativecommons.org/licenses/by-sa/4.0
Asuhan Gizi pada Pasien Diabetes Melitus, Hipertensi dan Penyakit Jantung Koroner NSTEMI : Studi Kasus
Diabetes mellitus accompanied by hypertension and coronary heart disease requires comprehensive nutritional management to improve clinical conditions and prevent further complications. This study aimed to describe the implementation of standardized nutritional care for a patient with diabetes mellitus, hypertension, and coronary heart disease with Non-ST Elevation Myocardial Infarction (NSTEMI) during hospitalization at a private hospital in Surabaya. The method used was a case study applying the standardized Nutrition Care Process, including assessment, diagnosis, intervention, monitoring, and evaluation. The assessment results showed that the patient experienced hyperglycemia with a random blood glucose level of 495 mg/dL and HbA1c of 12.5%, blood pressure of 170/95 mmHg, and required fluid restriction due to cardiovascular conditions. The nutritional diagnoses established included the need to reduce simple carbohydrate intake, sodium and cholesterol restriction, fluid restriction, and readiness for lifestyle modification. The nutritional intervention consisted of a diabetes mellitus diet, Dietary Approaches to Stop Hypertension (DASH), and a cardiac diet accompanied by nutrition education using leaflet media. Monitoring over three days showed a gradual improvement in food intake, sodium and cholesterol intake remained within recommended limits, and clinical improvement was observed, particularly in decreased blood pressure and blood glucose levels toward normal ranges. It can be concluded that the implementation of standardized nutritional care in patients with diabetes mellitus, hypertension, and NSTEMI coronary heart disease helped improve dietary intake and supported the stabilization of the patient’s clinical condition during hospitalization.
Copyright (c) 2026 Maulidina Maiyarani Amroe https://creativecommons.org/licenses/by-sa/4.0
Meta Analisis: Efektivitas Diet DASH terhadap Penurunan Tekanan Darah pada Penderita Hipertensi
Background: Hypertension is a global health issue that significantly contributes to morbidity and mortality. The DASH diet (Dietary Approaches to Stop Hypertension) has been recommended as a dietary approach to lower blood pressure, but findings across studies remain varied. Therefore, a meta-analysis was conducted to synthesize the existing evidence on the effectiveness of the DASH diet for blood pressure reduction in hypertensive patients. Objective: To systematically and quantitatively assess the effect of the DASH diet on lowering blood pressure in individuals with hypertension. Methods: This meta-analysis employed a random-effects model using Standardized Mean Difference (SMD) as the effect size. Data were extracted from six studies that met the inclusion criteria. OpenMEE software was used to calculate the pooled effect estimate and inter-study heterogeneity. Results: The findings showed that the DASH diet significantly reduced blood pressure, with an SMD of -1.219 (95% CI: -1.918 to -0.519; p < 0.001). Substantial heterogeneity was found across the included studies (I² = 88.24%; p < 0.001), indicating variations in population characteristics and study methodologies. Conclusion: The DASH diet is effective in lowering blood pressure in hypertensive patients and can be considered a key component of non-pharmacological intervention strategies. Despite the presence of heterogeneity, the consistent direction of effect supports its broader implementation with individual adaptations.
Copyright (c) 2026 Lindsay Ozora Sanyaezra Simanjuntak https://creativecommons.org/licenses/by-sa/4.0
Analisis Pemberian ASI Ekskluisf pada Ibu Pekerja di Wilayah Kerja Puskesmas Simpang Babat Tahun 2026
Exclusive breastfeeding is an important intervention to improve infant health status, growth, and development. However, the coverage of exclusive breastfeeding among working mothers remains suboptimal. This study aimed to analyze factors associated with exclusive breastfeeding among working mothers in the Simpang Babat Public Health Center working area, Penukal Abab Lematang Ilir (PALI) Regency. This study employed an analytic observational design with a cross-sectional approach conducted from February to June 2026. The study population consisted of 133 working mothers with infants aged 0–12 months, and a sample of 100 respondents was selected using proportional random sampling. Data were collected using a structured questionnaire and analyzed using the chi-square test and multiple logistic regression. The results showed that 55% of respondents did not practice exclusive breastfeeding. Bivariate analysis revealed that family economic status (p=0.001), maternal psychological condition (p=0.004), husband's support (p<0.001), workplace facilities support (p<0.001), and maternal knowledge (p=0.028) were significantly associated with exclusive breastfeeding. Multivariate analysis indicated that family economic status was the most dominant factor associated with exclusive breastfeeding (OR=15.866; 95% CI=3.618–69.582). In conclusion, exclusive breastfeeding among working mothers was associated with family economic status, maternal psychological condition, husband's support, workplace facilities support, and maternal knowledge. These findings highlight the need to strengthen breastfeeding education, increase husband involvement, and provide adequate lactation facilities in the workplace to support exclusive breastfeeding among working mothers.
Copyright (c) 2026 Gita Listawaty, Arie Wahyudi, Lilis Suryani https://creativecommons.org/licenses/by-sa/4.0
Hubungan Antara Masa Kerja dengan Carpal Tunnel Syndrome pada Pembatik Tulis di Kampung Batik Giriloyo Bantul
Batik tulis is one of Indonesia’s cultural heritages with high artistic and philosophical value, whose production process still relies heavily on manual activities using a traditional tool called canting. The batik-making process involves repetitive hand movements and prolonged working duration, which may increase the risk of musculoskeletal disorders, particularly Carpal Tunnel Syndrome (CTS). This study aimed to determine the relationship between working period and the incidence of Carpal Tunnel Syndrome among handwritten batik artisans in Giriloyo Batik Village, Imogiri, Bantul, and to describe the characteristics of working period and CTS incidence among the workers. This study employed a descriptive analytic quantitative method with a cross-sectional design. The research was conducted from July to August 2024 and involved 39 respondents selected based on inclusion and exclusion criteria. Data were collected using respondent identity questionnaires and the Boston Carpal Tunnel Questionnaire (BCTQ) to assess CTS symptoms. Data analysis included univariate and bivariate analyses using the chi-square test. The results showed that most respondents were female (97.3%), aged 40–60 years (64.1%), and worked less than 8 hours per day (66.7%). Most respondents with a working period of ≥4 years experienced CTS complaints (69.2%). Statistical analysis showed a significant relationship between working period and CTS incidence (p=0.028; p<0.05). The intensity of CTS symptoms also tended to increase with longer working periods. These findings highlight the importance of preventive efforts through ergonomic improvements and reducing exposure to repetitive movements among batik artisans.
Copyright (c) 2026 Surya Darma Budiono, Ana Budi Rahayu, Taufiek Hikmawan Yuliarto Benni Sambada https://creativecommons.org/licenses/by-sa/4.0
Literatur Review : Terapi Nonfarmakologis Kompres Aloe Vera sebagai Upaya Penanganan Demam pada Anak
Fever in children is an increase in body temperature caused by infection that requires appropriate management to prevent complications. One non-pharmacological therapy that can be used is an Aloe vera compress. This literature review aimed to determine the effectiveness of Aloe vera compress therapy in reducing body temperature in children with fever. The method used was a literature review conducted through article searches in the Google Scholar, PubMed, Garuda, and SINTA databases published between 2021 and 2026. Of the 80 articles identified, 10 articles met the inclusion criteria and were analyzed. The review results showed that Aloe vera compress therapy was effective in helping reduce children’s body temperature, with temperature reductions ranging from 0.1°C to 2.5°C. The effectiveness was influenced by the child’s condition, the cause of fever, the duration of the intervention, and the area of compress application. The mechanism of Aloe vera compress therapy works through its cooling effect, high water content, and conduction process that facilitates heat transfer from the body. In addition to reducing body temperature, this therapy also improved children’s comfort during fever. Therefore, Aloe vera compress therapy can be used as a safe, natural, and easily applicable supportive non-pharmacological intervention in the management of fever in children.
Copyright (c) 2026 Shabrina Safitri, Richa Cahya Setyowati, Nurkhalisah, Anisa Duwi Putri, Ni Wayan Wiwin Asthiningsih https://creativecommons.org/licenses/by-sa/4.0
Pengaruh Pemberian Terapi Sujok pada Pasien Nyeri Post General Anestesi
Postoperative pain is one of the most common complaints experienced by patients following surgical procedures performed under general anesthesia. Inadequate pain management may delay the recovery process, increase patient discomfort, and contribute to various physiological complications. One complementary therapy with potential analgesic benefits is Sujok therapy, a reflex point stimulation technique applied to the hands and feet that is believed to activate the body's natural pain-relief mechanisms. This study aimed to analyze the effect of Sujok therapy on pain intensity among post-general anesthesia patients at PKU Muhammadiyah Bantul Hospital. A quasi-experimental two-group pretest–posttest design was employed involving 30 respondents, who were allocated into intervention and control groups. Pain intensity was assessed using the Numeric Rating Scale (NRS) before and after the intervention. Data were analyzed using the Wilcoxon Signed-Rank Test and the Mann–Whitney U Test. The results showed that the mean pain score in the intervention group decreased from 5.87 ± 1.19 to 2.93 ± 1.03 (p = 0.001), whereas the control group showed a reduction from 5.73 ± 1.03 to 4.93 ± 1.03 (p = 0.042). The Mann–Whitney U Test revealed a significant difference in pain reduction between the two groups (p = 0.000). These findings indicate that Sujok therapy is effective in reducing pain among post-general anesthesia patients and has the potential to serve as a safe, simple, and easily applicable complementary intervention in perioperative nursing practice.
Copyright (c) 2026 Cahaya Nugraheni, Ririn Zuhairini https://creativecommons.org/licenses/by-sa/4.0
Uji Total Flavonoid dan Aktivitas Antioksidan Fraksi Aktif Kulit Kayu Manis (Cinnamomi burmannii cortex) sebagai Diabetic Ulcer
Diabetes mellitus is a chronic disease that can cause complications, one of which is diabetic ulcer, a wound that is difficult to heal due to increased oxidative stress. The use of natural ingredients such as cinnamon bark (Cinnamomi burmannii cortex), which is rich in flavonoids and phenolic compounds, has the potential to be an alternative supportive therapy due to its antioxidant activity. This research seeks to identify overall flavonoid levels and antioxidant properties within cinnamon bark active fractions while assessing its effectiveness for healing diabetic ulcers. The investigation involved laboratory experiments utilizing specific extraction techniques. Primary processing employed the maceration approach using 70% ethanol solvent, which was subsequently followed by a secondary liquid-liquid separation procedure to isolate desired chemical compounds. Total flavonoid amounts underwent analysis through AlCl3 colorimetry with UV-Vis spectrophotometry, while free radical scavenging capacity was evaluated employing DPPH methods and documented as IC50 values. The study revealed the ethyl acetate fraction contained peak flavonoid percentages (0.8637%) and exhibited the most effective antioxidant strength IC50 12.2716 ppm). These data imply that ethyl acetate extracts from cinnamon bark offer substantial viability for development as supplementary medicinal agents for diabetic ulcer care by effectively neutralizing oxidative damage during healing.
Copyright (c) 2026 Anggi Septya Insan, Novitaria Br Sembiring, Nerly Juli Pranita Simanjuntak https://creativecommons.org/licenses/by-sa/4.0
Perbandingan Efektivitas Virgin Coconut Oil dengan Herbal Mouthwash Lainnya terhadap Pengendalian Plak dan Gingivitis
Gingivitis is a common periodontal problem among university students and is closely associated with dental plaque accumulation. Although 0.2 percent chlorhexidine is effective as an antiplaque agent, long-term use may cause staining, dysgeusia, and mucosal irritation. This study aimed to compare the effectiveness of Virgin Coconut Oil (VCO) with other herbal mouthwashes for plaque control and gingivitis management. A Systematic Literature Review using narrative meta-synthesis was conducted based on the PRISMA 2020 protocol. Literature searches were performed in PubMed/MEDLINE and Scopus for publications from 2019 to 2024. From 1,247 initial records, 24 primary studies met the inclusion criteria based on the PICO framework. The synthesis showed that VCO through oil pulling reduced the Plaque Index by 20 to 52 percent and the Gingival Index by 18 to 47 percent from baseline. Neem, tea tree oil, Aloe vera, and green tea mouthwashes demonstrated effectiveness comparable to chlorhexidine, with better safety profiles. No head-to-head study directly compared VCO and herbal mouthwashes within one integrated design. These findings support herbal agents as promising adjunctive interventions in preventive dentistry for high-risk student populations.
Copyright (c) 2026 Fanny Nailatulizzah, Nur Hikmatang, Dwi Sashi Kirana Shohibul, Zhafirah Mahatma, Intan Permata Sari, Hamdana Raudyatuzahra Wahab, Fauziah Nuraini Masaruddin, Tenri Angka Muh. Ikbal https://creativecommons.org/licenses/by-sa/4.0
Katekin sebagai Intervensi Nutrisi Potensial untuk Menurunkan Tekanan Darah pada Penderita Hipertensi
Hypertension remains one of the foremost contributors to cardiovascular morbidity and mortality worldwide. Dietary-based preventive measures have increasingly emerged as a pivotal approach to blood pressure management, including the utilization of polyphenolic compounds such as catechins. Catechins have attracted considerable attention as a prospective nutritional intervention for blood pressure regulation. This literature review was undertaken to synthesize scientific evidence concerning the influence of catechins on blood pressure by examining studies retrieved from the PubMed and ScienceDirect databases using the keywords “catechin”, “blood pressure”, and “hypertension”. Findings derived from five selected studies indicate that catechins may facilitate blood pressure reduction through multiple physiological pathways, including the enhancement of nitric oxide bioavailability, improvement of endothelial performance, attenuation of oxidative stress and inflammatory responses, as well as modulation of neural regulatory mechanisms. Although the majority of investigations reported favorable outcomes, the magnitude of catechin efficacy appeared to be contingent upon dosage, molecular form, duration of intake, and participant characteristics. Consequently, the application of catechins as a potential nutritional strategy for hypertension management warrants careful dosage consideration and further validation through long-term investigations.
Copyright (c) 2026 Amanda Humaira Febriyanti https://creativecommons.org/licenses/by-sa/4.0
Hubungan Perilaku Merokok dengan Ketersediaan Ruang Terbuka Hijau di Area Publik pada Mahasiswa
Background: Air quality in public green open spaces (RTH) is often threatened by visitor smoking, which risks reducing the effectiveness of RTH as a health facility. This research seeks to explore the connection between visitor smoking behavior and the availability of green open spaces in public areas among Halu Oleo University students. Methods: This quantitative descriptive study used a cross-sectional, observational, and analytical approach. A group of 36 students was chosen employing a non-probability sampling method that relied on voluntary participation via surveys. Data collection was conducted on May 15, 2026, at Halu Oleo University, Kendari City. Analysis of the data used Fisher's Exact Test. Results: Descriptively, the majority of respondents (86.1%) felt disturbed by visitor smoking on campus. Furthermore, 97.2% of respondents assessed the availability and arrangement of green open spaces within the university environment as poor. Based on the results of bivariate analysis using Fisher's Exact Test, a p-value of 1.000 was obtained (p > 0.05). Conclusion: There is no significant relationship between visitor smoking behavior and the availability of green open spaces in public areas among students. This finding suggests that smoking activity in educational institutions is not determined by the physical condition of green open spaces, but is more predominantly influenced by internal factors such as attitudes and awareness, as well as weak oversight and implementation of Smoke-Free Area (KTR) policies.
Copyright (c) 2026 Sitti Rabbani Karimuna, Aulia Maghfirah Alifia, Agista Agista, Fifiani Fifiani, Fitriana Fitriana https://creativecommons.org/licenses/by-sa/4.0