Analisis Timbal (Pb) dan Cadmium (Cd) pada Jamu Tradisional Produk Teregistrasi BPOM dan Non Teregistrasi BPOM dengan Spektrofotometri Serapam Atom (SSA)

Authors

  • Arneta Hayfa Radanta Sekolah Tinggi Ilmu Kesehatan Nasional
  • Devi Indriyanti Sekolah Tinggi Ilmu Kesehatan Nasional
  • Grace Maria Intan Yulia Dewi Sekolah Tinggi Ilmu Kesehatan Nasional
  • Imelda Cantika Putri Sekolah Tinggi Ilmu Kesehatan Nasional
  • Pracellya Dyah Ayu Pramesthy Sekolah Tinggi Ilmu Kesehatan Nasional
  • Tirza Renitha Grace Modouw Sekolah Tinggi Ilmu Kesehatan Nasional
  • Yaafindra Nanda Arbella Sekolah Tinggi Ilmu Kesehatan Nasional
  • Abdul Rohman Adnan Prabowo Sekolah Tinggi Ilmu Kesehatan Nasional

DOI:

https://doi.org/10.55606/jurrike.v5i1.8298

Keywords:

Atomic Absorption Spectrophotometry, Cadmium, Heavy Metal Analysis, Lead, Traditional Herbal Medicine

Abstract

Jamu is a traditional medicine still widely consumed by the public, but it has the potential to be contaminated with the heavy metals lead (Pb) and cadmium (Cd), which are toxic and can cause health problems, particularly to the liver and kidneys. Heavy metal contamination can originate from raw materials grown in polluted environments and from processing, storage, and packaging that do not meet quality standards, particularly for products that have not undergone official supervision. This study aims to analyze the content of lead and cadmium metals in registered and unregistered herbal medicine products. The analysis was carried out using the Atomic Absorption Spectrophotometry (AAS) method after sample preparation through wet digestion using strong acid. Six herbal medicine dosage forms were analyzed, namely powder, chopped, pills, capsules, cream, and shake parem. Method validation included tests for linearity, precision, limit of detection, and limit of quantification to ensure the reliability of the analysis results. The results showed that all registered herbal medicine samples met the safety requirements for Pb and Cd. In contrast, several unregistered herbal medicine preparations, especially powder, chopped, and cream, did not meet the safety requirements for Cd, while the Pb levels in all samples met the safety requirements for Pb. These findings indicate that unregistered herbal medicines carry a higher risk of heavy metal contamination. Therefore, strengthening quality control, selecting safe raw materials, and increasing compliance with regulations are necessary to ensure the safety of herbal medicine consumption and protect public health.

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References

Alleandro, V., Talu, T., Kurniawan, H., & Nugraha, F. (2023). Identifikasi timbal dan verifikasi destruksi dengan metode spiking pada sampel kangkung darat di Kota Pontianak. 3(1), 69–76.

Badan Pengawas Obat dan Makanan Republik Indonesia. (2023). Peraturan Badan Pengawas Obat dan Makanan Nomor 29 Tahun 2023 tentang persyaratan keamanan dan mutu obat bahan alam. BPOM RI.

Fawehinmi, A. B., Lawal, H., & Chimezie, E. U. (2024). Determination of heavy metal contamination of some commercially available herbal preparations in Nigeria. 36(8), 46–54.

Jomova, K., Alomar, S. Y., Nepovimova, E., Kuca, K., & Valko, M. (2025). Heavy metals: Toxicity and human health effects. Archives of Toxicology, 99(1). Springer.

Mahmudi, M., Annisa, M., Farida, M., Yusuf, M., & Azhari, S. (2023). Assessing heavy metal contamination in traditional herbal medicine (jamu) by atomic absorption spectrophotometry. 1(1), 0–4.

Maulydia, N. B., Khairan, K., & Noviandy, T. R. (2023). Prediction of pharmacokinetic parameters from ethanolic extract of mane leaves (Vitex pinnata L.) in geothermal manifestation of Seulawah Agam Ie-Seu’um, Aceh. 1(1), 16–21.

Nakra, S., Tripathy, S., & Srivastav, P. P. (2025). Drying as a preservation strategy for medicinal plants: Physicochemical and functional outcomes for food and human health. Phytomedicine Plus, 5(2), 100762.

Noviandy, T. R., Maulana, A., Idroes, G. M., & Maulydia, N. B. (2023). Integrating genetic algorithm and LightGBM for QSAR modeling of acetylcholinesterase inhibitors in Alzheimer’s disease drug discovery. 1(2), 48–54.

Patiung, O., & Amamapare, P. (2022). Identifikasi kandungan logam berat Pb dan Cu pada sedimen daerah muara Sungai Amamapare, Timika, Papua. 3(1).

Setianingrum, T., Fitriana, A. S., & Nawangsari, D. (2025). Analisis cemaran logam berat (Pb, Cd, Zn) pada ikan tuna kemasan kaleng dengan metode spektrofotometri serapan atom (SSA).

Shinde, S. S., & Khulbe, P. (2023). Analytical method validation: A comprehensive review of current practices. XXI, 244–254.

Sugito, A., Marliyan, S. D., & H. D. A. (2022). Uji kinerja instrumen spektrofotometer serapan atom (AAS) Shimadzu 6650F terhadap logam Fe dan Zn pada kegiatan praktikum kimia anorganik di UPT Laboratorium Terpadu UNS. 5(2), 83–89.

Sulistyani, M., Kusumastuti, E., Huda, N., & Mukhayani, F. (2021). Method validation on functional group analysis of geopolymer with polyvinyl chloride (PVC) as additive using Fourier transform infrared. 10(3).

Sulistyani, M., Mahatmanti, F. W., Huda, N., & Prasetyo, R. (2025). Optimization of the performance of a microplate-type UV–Vis spectrophotometer as a protein content testing instrument based on green analytical chemistry (GAC). Indonesian Journal of Chemical Science, 14(3).

Susanto, A., Mulyani, T., & S. N. (2021). Validasi metode analisis penentuan kadar logam berat Pb, Cd, dan Cr terlarut dalam limbah cair industri tekstil dengan metode inductively coupled plasma optical emission spectrometry. 19(1), 191–200.

Taufiq, M. (2023). Metode destruksi gelombang mikro menggunakan variasi konsentrasi asam nitrat untuk penentuan logam Cd dan Pb dalam produk makanan bayi. 17(1).

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Published

2026-01-30

How to Cite

Arneta Hayfa Radanta, Devi Indriyanti, Grace Maria Intan Yulia Dewi, Imelda Cantika Putri, Pracellya Dyah Ayu Pramesthy, Tirza Renitha Grace Modouw, … Abdul Rohman Adnan Prabowo. (2026). Analisis Timbal (Pb) dan Cadmium (Cd) pada Jamu Tradisional Produk Teregistrasi BPOM dan Non Teregistrasi BPOM dengan Spektrofotometri Serapam Atom (SSA). JURNAL RISET RUMPUN ILMU KEDOKTERAN, 5(1), 286–300. https://doi.org/10.55606/jurrike.v5i1.8298

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