Anemia Hemolitik Disebabkan Infeksi Kongenital Citomegalovirus

Indah Afriwanty Simatupang; Ricke Loesnihari; Wan Tysa Muhaira

doi:10.55606/jurrike.v4i2.6279

Authors

Indah Afriwanty Simatupang Institut Kesehatan Helvetia
Ricke Loesnihari Rumah Sakit Umum Pusat Haji Adam Malik
Wan Tysa Muhaira Institut Kesehatan Helvetia

DOI:

https://doi.org/10.55606/jurrike.v4i2.6279

Keywords:

anti CMV IgG, CMV, IgG CMV (Avidity)

Abstract

Hemolitic anemia is a condition of anemia caused a shortened lifespan of eritrocytes due to an increase in a rate of eritrocytes destruction higer than eritrocytes production in the bone marrow. Congenital Citomegalovirus Infection (CMV) is one of the most common viral infections that causes congenital infections. CMV is transmitted by contact with an individual who carries CMV infection. Approximatelly 90% of congenitally infected infants develop symptoms at birth. Jaundice, petechiae, and hepatosplenomegaly are the three most common sequences in infants. Congenital CMV infection can be diagnosed by isolating the virus by urine and saliva within first three weeks of life. Case Description A 24-day-old baby comes with jaundice all the body since the age of 14 days. Innitially Indah Afriwanty Simatupang, Ricke Loesnihari. Congenital Citomegalovirus Infection., light carried out at hospital but there was no change, the the patient was referred to Adam Malik Hospital. From the examination it was found thrombocytopenia, metabolic acidosis, increased SGOT and SGPT, increased total bilirubin and direct bilirubin, decreased procalcitonin, positive anti CMV IgG, and positive IgG CMV (Avidity). CONCLUSION Based on the history of physical and laboratory examination, its supports the diagnosis of Congenital Cytomegalovirus Infectios.

Downloads

Download data is not yet available.

References

Akhter, K., & Wills, T. S. (2016, November 17). Cytomegalovirus. eMedicine. https://emedicine.medscape.com/article/215702

Akpan, U. S., & Pillarisetty, L. S. (2023). Congenital cytomegalovirus infection. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK541003/

D’Oronzio, U., Arlettaz, M. R., & Hagmann, C. (2015). Congenital cytomegalovirus infection. Swiss Society of Neonatology.

Emery, V. C., & Lazzarotto, T. (2017). Cytomegalovirus in pregnancy and the neonate. F1000Research. https://doi.org/10.12688/f1000research.10276.1

Greer, J. P., Foerster, J., Lukens, J. N., & Perkins, S. L. (2003). Wintrobe’s clinical hematology (December, pp. 1929–1950).

Johnson, J., Anderson, B., & Pass, R. F. (2012). Prevention of maternal and congenital cytomegalovirus infection. Clinical Obstetrics and Gynecology, 55(2), 521–530.

Kim, C. S. (2010). Congenital and perinatal cytomegalovirus infection. Korean Journal of Pediatrics, 51(1), 14–20.

Leung, A. K. C., Sauve, R. S., & Davies, H. D. (2003). Congenital cytomegalovirus infection. Journal of the National Medical Association, 95(3), 213–218.

Parmigiani, S. V., Barini, R., Costa, S. C. B., Amaral, E., Silva, J. C. G., & de Carvalho Pinto, E. J. L. (2003). Accuracy of the serological ELISA test compared with the polymerase chain reaction for the diagnosis of cytomegalovirus infection in pregnancy. São Paulo Medical Journal, 121(3), 97–101.

Plosa, E. J., Esbenshade, J. C., Fuller, M. P., Weitkamp, J.-H., & Plosa, D. (2012). Cytomegalovirus infection. Pediatrics in Review, 33(4), 156–163. http://pedsinreview.aappublications.org/

Pratama, B. F. (2018). Infeksi cytomegalovirus kongenital. Jurnal Kesehatan Melayu, 1(2), 114.

Pugel, E. P., & Cekinović, D. (2011). Pathogenesis of congenital cytomegalovirus infection of the central nervous system. Periodicum Biologorum, 113(1), 51–60.

Rampengan, N. H. (2015). Diagnosis infeksi HIV pada bayi dan anak. Jurnal Biomedik, 7, 137–143.

Ross, S. A., Ahmed, A., Palmer, A. L., et al. (2014). Detection of congenital cytomegalovirus infection by real-time polymerase chain reaction analysis of saliva or urine specimens. Journal of Infectious Diseases, 210(9), 1415–1418.

Schleiss, M. R. (2018). Congenital cytomegalovirus: Impact on child health. Contemporary Pediatrics, 35(7), 16–24.

Scott, J. H., & David, K. W. (2016). Advances in the prevention and treatment of congenital cytomegalovirus infection. Current Opinion in Pediatrics, 28(1), 81–85.

Stehel, E. K., & Sanchez, P. J. (2005). Cytomegalovirus infection in the fetus and neonate. NeoReviews, 6(1), 38–45.